yep, I guess I'm old school where your tone comes from a great guitar, great amp, very few fx in the signal chain, and a lot of hard work to become a great player. If you try to get your tone strictly from a pod or similar, it can sound very good, but often (not always though) the best guitar tone comes from great micing of the amp of a guitarist who's put time into making a great tone come from a real amp. That being said, if you use a pod and a home stereo (or pa) to create your live guitar tone, as long as it sounds amazing, you can work well with that too.
I was one of the first live gig guitarists in vancouver in the 80s to go ampless with an fx-500 and a lot of carefully setup patches that used my own fake amp sim through equing. It sounded great, but finally I went back to using an amp since I honestly get more true tube warmth, control, and most importantly monitoring of my own real tone from my amp when live or in the studio. As stated, I now use an ME-50, but whatever works for you. In the 80s I used
my chandler tube driver to give me real tube tone wiht
my fx-500, these days I use
a vox valvetronix amp. whatever works for you. best idea, experiment with the toys at the store. ME-50 doesn't have much of an amp sim in it, except through the headphone output (which does sound great but is intended for headphone listening and may not work great into a board direct, I haven't tried).
Cheers,
Don