MD-421 sounds very good with saxaphone. In my opinion, there is really no best mic for any one application. It depends on what you are looking to accomplish. I know about the MD-421, as I had my own sound reinforcement company for a while and was lucky enough to get a bunch of MD-421's at a good price. I used them on damn near everything in the beginning. I found them good on saxaphone, male vocals, tom-toms, floor toms, guitar speaker cabinets... on an on... I got the idea to use 421's on so many things from looking at the stage at Grateful Dead concerts in the 1980's. The engineer, Dan Healy, used them on almost everything! Kick drum, toms, all the various percussion, all the vocals and Jerry Garcia's guitar amp speakers. You have to check them against each other periodically, as the can "go bad." I'm not sure what it is, but they lose their sound sometimes.