Plugins not having sound in cubaseai8

I have a project going in cubasele8 and maxed out the instrument and audio tracks..Plus used a lot of instrument and effects plugins..Everything was fine with my uca222 behringer interface until the drum track started "stuttering" .I adjusted something in the driver to fast instead of normal and that fixed it. Then out of nowhere the instrument plugins failed to have any audio.The event light was flashing indicating it was functioning but no sound..The sound bar indicators in cubase worked too.I tried changing channels and outputs but nothing. It seems as soon as I use automation the plugins shut down..They work as long as I don't use the red or green automation buttons..but I need to use automation..Do you have any idea what this could be..Halion sonic se drops out too.
 
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