Need more info. Are you tracking, and trying to get a live effect on your performance? If you're tracking, you need to tweak your drivers or adjust some buffer settings or something to get latency as low as possible. That can be very difficult if your hardware isn't 1/2 way current. And you'll ALWAYS have latency anyway, you can't completely get rid of it. You can possibly get it down to a negligible level.
Or are you mixing into a track that's already recorded? If you're mixing, then your PC simply can't keep up with processing the track and plugin in real time. Your PC simple can't keep up. Are you recording at 44.1/24? If you're sampling at 96k+, then maybe your PC's hard drive i/o can't keep up, record at 44.1/24 from now on. Any DAW will let you render the track with fx as a new track, then your PC won't have to process the track and plugin every time while playing the song back. You'll have to cut whatever your bottleneck is.