Plenty good.....Just make sure to match up your impedances correctly.......when in doubt, always set the amp on "4" ohms. For the best possible set up though you would ideally match the impedances evenly. Since the Mesa head is more than likely a mono head, you will be using either the 4 or 16 (Mono / Mono )setting on your cabinet. It doesn't matter which one you use, as long as you match the evenly.........so is you are using the 4 ohm main out on your head, you would select the 4 ohm mono input on your cab........and the same would be true for 16 ohms.
Rick