I don't even know what the spacing is on my guitars.
I have one of the Vintage54 strats, The radius is 7 1/2 inches, but I dont know about the spacing. I know it doesn't give me a problem playing. I have an ASAT Special and an old G&L Legacy. Flatter radius, but I don't think they are much different from the strat.
The biggest change is when I pick up my Taylor 310ce. Its got a really wide fretboard which is fine for fingerpicking, but not as comfortable or easy to do things like barre chords.
I seem to adjust to things like spacing and radius but I really hate the necks on PRS guitars. Something about the back shape doesn't fit well for me. Its especially bad on the SE models.