I've always liked Seymour Duncan pickups. I had a 335-style guitar which I put a '59 in the neck position, and a 'Mag' at the bridge with a coil tap on it.
I was very happy with the way it sounded - real nice bluesy tone out of the neck p/up, and a nice edgy ballsy sound out of the bridge h/bucker, and it thinned out nicely for more of a Tele/Strat single coil sound with the tap in.
Both p/ups on was a good jangly rhythm sound and it got real jangly with the bridge p/up as a single coil.
Also had a Duncan 'custom' on another guitar in the neck position - it had a litle more power than the '59 and so was able to create a bit more distortion.
You might want to try this set up:
Duncan Custom on the neck with coil tap
Duncan Alnico II strat replacement pickup in the middle
Duncan Mag at the bridge
Install a five-way switch and have the best of both worlds - the Mag as a single and the middle p/up will sound very Stratty, but the Custom split and the middle is a little more ballsy than the same Strat configuration.
Hope this helps,
foo
[This message has been edited by foo (edited 04-27-2000).]