Well...I finally got my Lexicon U22 back from lexicon support. They completely replaced the motherboard. And it sounded better, but in an A/B test with the FT600...hands down the FT600 wins for better sounding pres! Warm and analog sounding compared to the U22. I had no idea what I was missing!
As far as the build quality, I"m over the swirl thing and just let it go. The plasticky feel of the unit kinda sucks but I haven't seen anything not working or breaking. I think for my desktop/home needs, it will be fine. Definitely NOT for pro use! But the sound quality is there for sure!!
I love the multiple monitor function! I have it set up as my iMacs output and input via the control panel. I have noticed that when I restart I have to open the sound control panel and reselect it as my IO. I have all my sound going thru the interface and have hooked up my CREATIVE brand powered speakers/sub to the B monitor button, my M-Audio BX5as to the A button. It's nice to A/B mixes. I listen to my iTunes and all computer stuff via the interface now. NO the keyboard buttons no longer control volume or mute But the big volume dial on the interface is right there and easy to dial up or down. I enjoy using my headphones late at night to watch or listen while the rest of the family is asleep.
The control panel (software mixer) was a little confusing to me at first but I'm getting used to it.
All in all, I think it's a good unit. I paid $375 at sweet water for it. I wouldn't pay more!
Good luck, let me know if I can help more!