Best DAW setup

[babylon303]

Hullo all... Am new to this forum, but have been recording for years on and off..

I have a DAW (Cubase) based setup at home. When I had my old studio set up, I'd route all my synths/keyboars through channels in my mixing desk, along with my PC, then the main outs on the desk would go to my amp.

Now, I've set it up so that all my gear goes through my desk, then the outs go to my PC, which mixes both my synths and PC Audio together, then goes out to my amp.

Can anyone offer pro's and con's to each method of setup, and which would be more preferrable?

Thanks!