I have triple-monitor setup for other work that I do, 24" center with 19" left and right. The left and right monitors are in the position where studio monitors are usually located. Currently I have my small M-Audio AV30's below the main monitor. I am looking to upgrade and improve sound quality. If I go with a larger studio monitors, it is better to turn them sideways to prevent them from being blocked by the monitors and perhaps angle them up or better to position them to the left/right of the wing monitors - they would be 5 feet apart and angled in quite a bit.