Wow, 4 gauge!
This is always a hotly debated issue, but when you look at the science, speaker cable has no perceptible effect on sound.
The effect of all the various components inside a loudspeaker (wires, inductors, capacitors, resistors, solder joints, etc.) completely dwarfs the effect of the relatively tiny variations in resistance, capacitance, inductance and skin effects between normal speaker wires whatever the cost or level of "engineering". The magnitude of these speaker wire properties are well within the "noise" (1 standard deviation) compared to the tolerances of even the tightest matched drivers and crossover components. Speaker wire effects only become audible when you get into the extremes of long runs and/or thin gauges.
Beyond this, simple variations in the weather or altitude cause changes in pressure and sound velocity which alter speaker parameters and also completely obliterates the miniscule effect of wire.
For developing and testing my speakers I use 2 meters of
12 gauge tinned OFHC (Oxygen Free High Conductivity) copper wire with PVC insulation. Not that it makes any difference, but saying I use a "standard" seems to give a warm fuzzy to those who can't let go of their superstitions.
That huge wire you're talking about is complete overkill, not to mention cumbersome. Whatever you use, just give a quick brush on the exposed ends with sandpaper or steel wood to remove any oxidation, then give a tight clamp with the connectors.
Oh, and watch your back lugging that wire home!
barefoot