After spending half my life sitting down working they tell me now that it's better to be standing. So, if you can create a workstation that lets you work standing (as I saw folks doing just before I left that behind), and it's suitably quiet, and you can be still enough to maintain good audio quality for the length of your broadcast, I'd sure give it a try.
P.S. When my wife went back to school for a few years, a few years back, I just got her a tall drafting chair and built a couple stands for the monitor and keyboard so she could switch between standing and sitting when she wanted.