I'd say keep to 44.1 for music. If you can, and have the space to do so, record at 24, 32... or whatever you can put it to. Then bring it down to 16 after recording to put to CD. If you are doing audio for DVD/film, 48 is definitely better for you than 44.1.
3.8GHz i5 760/8GB RAM/Samsung 1TB Spinpoint F3s.
Shine WEB45, Vintage Metal Axxe Wraith, Stagg, Aria Pro II JS, Yamaha PSR-275, EKO Acoustic.
Studio Projects B1.
Studio One, Reaper.
Metal, Jazz, Ambient, Trance.