Also, think about the upgrades. An upgrade for cubase is a couple hundred bucks. an upgrade for nuendo id almost $1000.
The only reason I use nuendo is because I started with version 1, when there was a real difference between it and cubase. After that, the upgrade path always made more sense than buying into cubase at full price. Ten years into it, I really wish I would have gone with cubase in the first place.