I've owned a Mesa Triple Rec for around a year, and while at first it seemed the cat's ass compared to anything else I'd played, I'm now beginning to fully realize it's limitations and it's pissing me off! At first, the high-gain/scooped mids/smooth distortion seems like the "tone of the Gods", but now that I'm actually playing some real music with real dynamics (and lots of solos!), I find it's tone a bit... lacking. It's got no balls! I recently re-tubed it, which it desperately needed, but that still hasn't given me the extreme distorted mega huge screaming raging explosion tone I'm looking for. It's more of a nu-metallish rhythm-guitar mediocre scooped tone, which I largely attribute to it's terrible "Mid" knob. It's like it's just boosting the boomy shit frequencies that most of us cut out of a mix right away. There aren't any medium-high mids at all!
That said, what should I be looking at to get that mega-huge ballsy angry tone? Somewhere between Bloodbath and Early-to-Mid Metallica? Something like Opeth!!! I play a brand of metal somewhere between 80's Metallica, Opeth, Between the Buried and Me, and At the Gates, with an extremely fair helping of sweet solos!
*Edit: to clarify, I've been playing guitar for around 7 years, and have been touring for the last two, so I'm not a n00b playing-wise. Tone-wise, I'm in the crowd of, "I don't know, but I know what I like!". I'm just starting to get into playing with things like my amp/pickups/strings/etc. more than a little, and I want to go the right direction right away vs. trying 20 different amps just to figure out my pickups were the problem the whole time or something!